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GTX102326 WB Image
GTX102326 WB Image
GTX102326 WB Image

EEF1A2 antibody

Research Use Only
GTX102326
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    EEF1A2 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.21 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival. Losada A et al., 2018 Nov, Br J Cancer
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  • Comparative Proteomic and Transcriptomic Analysis of Follistatin-Induced Skeletal Muscle Hypertrophy. Barbe C et al., 2017 Oct 6, J Proteome Res
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  • EEF1A2 triggers stronger ERK mediated metastatic program in ER negative breast cancer cells than in ER positive cells. Hassan MK et al., 2020 Dec 1, Life Sci
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  • Expression pattern of EEF1A2 in brain tumors: Histological analysis and functional role as a promoter of EMT. Hassan MK et al., 2020 Apr 1, Life Sci
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  • In vivo characterization of the role of tissue-specific translation elongation factor 1A2 in protein synthesis reveals insights into muscle atrophy. Doig J et al., 2013 Dec, FEBS J
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  • Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin. Losada A et al., 2016 Oct 7, Sci Rep
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