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GTX100448 WB Image
GTX100448 WB Image
GTX100448 WB Image

EGFR antibody [C2C3], C-term

Research Use Only
GTX100448
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    EGFR antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.28 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat Methods
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  • EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation. Abdi K et al., 2019 Aug 20, Cell Rep
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  • Quercetin Reverses Rat Liver Preneoplastic Lesions Induced by Chemical Carcinogenesis. Carrasco-Torres G et al., 2017, Oxid Med Cell Longev
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  • Salvianolic acid B maintained stem cell pluripotency and increased proliferation rate by activating Jak2-Stat3 combined with EGFR-Erk1/2 pathways. Liu CH et al., 2014, Cell Transplant
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  • Synergistic inhibitory effects of cetuximab and curcumin on human cisplatin-resistant oral cancer CAR cells through intrinsic apoptotic process. Chen CF et al., 2018 Nov, Oncol Lett
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