Overview
- SupplierGeneTex
- Product NameEGFR antibody [N1-2], N-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.04 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A new type of gadodiamide-conjugated amphiphilic chitosan nanoparticle and its use for MR imaging with significantly enhanced contrastability. Huang WT et al., 2019 Jan 1, Carbohydr PolymRead more
- Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. Li J et al., 2020 Jul 15, J EthnopharmacolRead more
- Enhancement by Nano-Diamino-Tetrac of Antiproliferative Action of Gefitinib on Colorectal Cancer Cells: Mediation by EGFR Sialylation and PI3K Activation. Chang TC et al., 2018 Dec, Horm CancerRead more
- HER4 promotes the progression of colorectal cancer by promoting epithelial-mesenchymal transition. Jia X et al., 2020 Apr, Mol Med RepRead more
- NF-kappaB-induced KIAA1199 promotes survival through EGFR signalling. Shostak K et al., 2014 Nov 4, Nat CommunRead more
- Novel Pyropheophorbide Phosphatydic Acids Photosensitizer Combined EGFR siRNA Gene Therapy for Head and Neck Cancer Treatment. Yeh CH et al., 2021 Sep 9, PharmaceuticsRead more
- OFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblasts. Jerman S et al., 2014, PLoS OneRead more
- PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. Jao TM et al., 2021 Feb 28, Cancer LettRead more
- Salvianolic acid B maintained stem cell pluripotency and increased proliferation rate by activating Jak2-Stat3 combined with EGFR-Erk1/2 pathways. Liu CH et al., 2014, Cell TransplantRead more
- Sialylation regulates myofibroblast differentiation of human skin fibroblasts. Sasaki N et al., 2017 Apr 18, Stem Cell Res TherRead more