Bio-Connect
GTX121919 IHC-P Image
GTX121919 IHC-P Image
GTX121919 IHC-P Image

EGFR antibody [N1-2], N-term

Research Use Only
GTX121919
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    EGFR antibody [N1-2], N-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1.04 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A new type of gadodiamide-conjugated amphiphilic chitosan nanoparticle and its use for MR imaging with significantly enhanced contrastability. Huang WT et al., 2019 Jan 1, Carbohydr Polym
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  • Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. Li J et al., 2020 Jul 15, J Ethnopharmacol
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  • Enhancement by Nano-Diamino-Tetrac of Antiproliferative Action of Gefitinib on Colorectal Cancer Cells: Mediation by EGFR Sialylation and PI3K Activation. Chang TC et al., 2018 Dec, Horm Cancer
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  • HER4 promotes the progression of colorectal cancer by promoting epithelial-mesenchymal transition. Jia X et al., 2020 Apr, Mol Med Rep
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  • NF-kappaB-induced KIAA1199 promotes survival through EGFR signalling. Shostak K et al., 2014 Nov 4, Nat Commun
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  • Novel Pyropheophorbide Phosphatydic Acids Photosensitizer Combined EGFR siRNA Gene Therapy for Head and Neck Cancer Treatment. Yeh CH et al., 2021 Sep 9, Pharmaceutics
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  • OFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblasts. Jerman S et al., 2014, PLoS One
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  • PCDH10 exerts tumor-suppressor functions through modulation of EGFR/AKT axis in colorectal cancer. Jao TM et al., 2021 Feb 28, Cancer Lett
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  • Salvianolic acid B maintained stem cell pluripotency and increased proliferation rate by activating Jak2-Stat3 combined with EGFR-Erk1/2 pathways. Liu CH et al., 2014, Cell Transplant
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  • Sialylation regulates myofibroblast differentiation of human skin fibroblasts. Sasaki N et al., 2017 Apr 18, Stem Cell Res Ther
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