EHMT2 antibody, PAb

Biorbyt

EHMT2 antibody, PAb

16

Western Blot

WB:1:1000-1:5000 WB

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Rabbit polyclonal to EHMT2.Euchromatic histone-lysine N-methyltransferase 2 (EHMT2) belongs to the histone-lysinemethyltransferase family, Suvar3-9 subfamily. EHMT2 specifically mono-and dimethylates Lys-9 ofhistone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tagfor epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT2also weakly methylates Lys-27 of histone H3 (H3K27me). In addition, EHMT2 is required for DNAmethylation, which is independent of its histone methyltransferase activity. Furthermore, EHMT2methylates non-histone proteins, including p53/TP53, CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6,KLF12 and itself.

Human

2°C to 8°C,-20°C

12352203