GTX118895 ICC/IF Image
EIF3A antibody [N1N2], N-term
GTX118895
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameEIF3A antibody [N1N2], N-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.96 mg/ml
- IsotypeIgG
- Scientific DescriptionComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Regulation of hepatitis C virus translation initiation by iron: role of eIF3 and La protein. Wang Q et al., 2012 Aug, Virus ResRead more