GTX108204 IHC-P Image
Endothelin B Receptor antibody [C3], C-term
GTX108204
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameEndothelin B Receptor antibody [C3], C-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.52 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Airborne fine particulate matter alters the expression of endothelin receptors in rat coronary arteries. Xiao X et al., 2016 Nov, Environ PollutRead more