GTX30614 WB Image
EP300 antibody [RW128]
GTX30614
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mammals, Mouse, Primate, Rat
Overview
- SupplierGeneTex
- Product NameEP300 antibody [RW128]
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRW128
- Concentration1 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionThis gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq]
- ReactivityHuman, Mammals, Mouse, Primate, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203