GTX113094 IHC-P Image
GTX113094 IHC-P Image
ERK2 antibody [N2C3]
GTX113094
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameERK2 antibody [N2C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 18beta-glycyrrhetinic acid inhibits migration and invasion of human gastric cancer cells via the ROS/PKC-alpha/ERK pathway. Cai H et al., 2018 Jan, J Nat MedRead more
- 2,3,5,4-Tetrahydroxystilbene-2-O-beta-glucoside Isolated from Polygoni Multiflori Ameliorates the Development of Periodontitis. Chin YT et al., 2016, Mediators InflammRead more
- A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat MethodsRead more
- A study of the spatial protein organization of the postsynaptic density isolated from porcine cerebral cortex and cerebellum. Yun-Hong Y et al., 2011 Oct, Mol Cell ProteomicsRead more
- Actions of l-thyroxine and Nano-diamino-tetrac (Nanotetrac) on PD-L1 in cancer cells. Lin HY et al., 2016 Oct, SteroidsRead more
- Loss of endosomal recycling factor RAB11 coupled with complex regulation of MAPK/ERK/AKT signaling in postmortem spinal cord specimens of sporadic amyotrophic lateral sclerosis patients. Mitra J et al., 2019 Jun 13, Mol BrainRead more
- Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers. Nana AW et al., 2018 Oct, Horm CancerRead more
- Novel Role for miR-1290 in Host Species Specificity of Influenza A Virus. Huang SY et al., 2019 Sep 6, Mol Ther Nucleic AcidsRead more
- PM2.5 facilitates IL-6 production in human osteoarthritis synovial fibroblasts via ASK1 activation. Liu JF et al., 2021 Mar, J Cell PhysiolRead more
- Quercetin 3-O-methyl ether protects FL83B cells from copper induced oxidative stress through the PI3K/Akt and MAPK/Erk pathway. Tseng HL et al., 2012 Oct 1, Toxicol Appl PharmacolRead more