GTX41198 ELISA Image
Factor VII antibody [RFF-VII/1]
GTX41198
ApplicationsWestern Blot, ELISA, RadioImmunoAssay
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameFactor VII antibody [RFF-VII/1]
- Delivery Days Customer10
- ApplicationsWestern Blot, ELISA, RadioImmunoAssay
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRFF-VII/1
- Concentration1 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionThis gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203