GTX42345 FACS Image
GTX42345 FACS Image
Fas Ligand antibody [10F2] (Low endotoxin, azide free)
GTX42345
ApplicationsFlow Cytometry, ImmunoPrecipitation, ELISA, Neutralisation/Blocking, Other Application
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameFas Ligand antibody [10F2] (Low endotoxin, azide free)
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoPrecipitation, ELISA, Neutralisation/Blocking, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10F2
- Concentration1 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionThis gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Fas/FasL interaction mediates imbalanced cytokine/cytotoxicity responses of iNKT cells against Jurkat cells. Dou R et al., 2018 Jul, Mol ImmunolRead more
- Rabbit antithymocyte globulin induces human lymphocyte activation, proliferation, and apoptosis in the absence of complement: an experimental study. Tan X et al., 2021 May, Transpl IntRead more