GTX109833 IHC-P Image
GTX109833 IHC-P Image
Fatty Acid Synthase antibody [N1], N-term
GTX109833
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameFatty Acid Synthase antibody [N1], N-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.2 mg/ml
- IsotypeIgG
- Scientific DescriptionThe enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- 3,5-Dicaffeoylquinic Acid Lowers 3T3-L1 Mitotic Clonal Expansion and Adipocyte Differentiation by Enhancing Heme Oxygenase-1 Expression. Raineri A et al., 2021 Aug 19, MoleculesRead more
- A novel small molecule liver X receptor transcriptional regulator, nagilactone B, suppresses atherosclerosis in apoE-deficient mice. Gui Y et al., 2016 Oct, Cardiovasc ResRead more
- Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats. Garcia-Arroyo FE et al., 2019 Oct 11, BiomoleculesRead more
- Clinical importance of FASN in relation to HIF-1alpha and SREBP-1c in gastric adenocarcinoma. Ezzeddini R et al., 2019 May 1, Life SciRead more
- Dietary supplementation with myo-inositol reduces hepatic triglyceride accumulation and expression of both fructolytic and lipogenic genes in rats fed a high-fructose diet. Shimada M et al., 2017 Nov, Nutr ResRead more
- Fenofibrate induces human hepatoma Hep3B cells apoptosis and necroptosis through inhibition of thioesterase domain of fatty acid synthase. You BJ et al., 2019 Mar 1, Sci RepRead more
- Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1alpha-dependent pathway. Jhuang HJ et al., 2015 Apr 10, OncotargetRead more
- Loss of Acot12 contributes to NAFLD independent of lipolysis of adipose tissue. Park S et al., 2021 Jul, Exp Mol MedRead more