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GTX117774 WB Image
GTX117774 WB Image
GTX117774 WB Image

FBXO22 antibody [N3C3]

Research Use Only
GTX117774
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    FBXO22 antibody [N3C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.29 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Two transcript variants encoding different isoforms exist for this gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer. Johmura Y et al., 2018 Dec 3, J Clin Invest
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  • Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1. Lignitto L et al., 2019 Jul 11, Cell
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