FGF21 antibody, PAb
ORB27781
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityMouse
Overview
- SupplierBiorbyt
- Product NameFGF21 antibody, PAb
- Delivery Days Customer10
- ApplicationsWestern Blot, ELISA
- Applications SupplierELISA, WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionFibroblast growth factor 21(FGF21) is a novel protein that has been implicated in the regulation of lipid and glucose metabolism under fasting and ketotic conditions. In murine models, FGF21 is predominantly expressed in liver, but it also expressed in adipose tissue and pancreatic beta-cells. FGF21 stimulates glucose uptake in adipocytes. It also protects animals from diet-induced obesity when overexpressed in transgenic mice and lowers blood glucose and triglyceride levels when administered to diabetic rodents. When administered daily for 6 weeks to diabetic rhesus monkeys, FGF21 caused a dramatic decline in fasting plasma glucose, fructosamine, triglycerides, insulin, and glucagon. Furthermore, elevated plasma FGF21 concentrations in humans appear to be related to the presence of hepatic and peripheral insulin resistance.
- SourceThis antibody can be used at 0.2microg/mL - 0.5microg/mL with the appropriate secondary reagents to detect mouse FGF21.
- ReactivityMouse
- UNSPSC12352203