GTX112939 IHC-P Image
Filamin A antibody [C2], C-term
GTX112939
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameFilamin A antibody [C2], C-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.42 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- The putative involvement of actin-binding proteins and cytoskeleton proteins in pathological mechanisms of ketamine cystitis-Revealed by a prospective pilot study using proteomic approaches. Yang HH et al., 2017 Mar, Proteomics Clin ApplRead more