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GTX101206 ICC/IF Image
GTX101206 ICC/IF Image
GTX101206 ICC/IF Image

Filamin B antibody [N1], N-term

Research Use Only
GTX101206
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Filamin B antibody [N1], N-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    10 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network. Artym VV et al., 2015 Feb 2, J Cell Biol
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  • Filamin B Loss-of-Function Mutation in Dimerization Domain Causes Autosomal-Recessive Spondylocarpotarsal Synostosis Syndrome with Rib Anomalies. Yang CF et al., 2017 May, Hum Mutat
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  • Mechanisms and Effects on HBV Replication of the Interaction between HBV Core Protein and Cellular Filamin B. Li Y et al., 2018 Apr, Virol Sin
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