FLT1 antibody, PAb
ORB27611
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
Overview
- SupplierBiorbyt
- Product NameFLT1 antibody, PAb
- Delivery Days Customer10
- ApplicationsWestern Blot
- Applications SupplierWestern blot - 0.1-0.5 μg/ml - Human - - - WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration500 ug/ml
- HostRabbit
- IsotypeIgG
- Scientific DescriptionRabbit Polyclonal to FLT1. Growth arrest and DNA-damage-inducible protein GADD45 alpha (GADD45A) is a protein that in humans is encoded by the GADD45A gene. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. Papathanasiou et al. (1991) demonstrated that the GADD45 gene is located on 1p34-p12. Sequence analysis of human and hamster cDNA clones demonstrated that the gene has been highly conserved and encodes a novel 165-amino acid polypeptide. Northern blot analysis detected moderate expression of a 1.4-kb GADD45A transcript in heart, skeletal muscle, and kidney, with little or no expression in brain, placenta, lung, liver, and pancreas. Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203