Overview
- SupplierGeneTex
- Product NameFOG2 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.96 mg/ml
- IsotypeIgG
- Scientific DescriptionThe zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- CRISPR/CAS9 ablation of individual miRNAs from a miRNA family reveals their individual efficacies for regulating cardiac differentiation. Zhang Z et al., 2018 Apr, Mech DevRead more
- MicroRNA-200c Promotes Suppressive Potential of Myeloid-Derived Suppressor Cells by Modulating PTEN and FOG2 Expression. Mei S et al., 2015, PLoS OneRead more
- Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension. Kumarasamy S et al., 2015 Feb 17, Nat CommunRead more
- The miR-17-92 cluster regulates FOG-2 expression and inhibits proliferation of mouse embryonic cardiomyocytes. Xiang R et al., 2012 Feb, Braz J Med Biol ResRead more