GTX105822 IHC-P Image
GTX105822 IHC-P Image
Folate Receptor beta antibody
GTX105822
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameFolate Receptor beta antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.98 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 18F-AzaFol for Detection of Folate Receptor-beta Positive Macrophages in Experimental Interstitial Lung Disease-A Proof-of-Concept Study. Schniering J et al., 2019, Front ImmunolRead more
- Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size. Meredith M et al., 2016 Jun, Biol ReprodRead more
- Identification of a PET Radiotracer for Imaging of the Folate Receptor-alpha: A Potential Tool to Select Patients for Targeted Tumor Therapy. Guzik P et al., 2021 Oct, J Nucl MedRead more
- Nanovector Assembled from Natural Egg Yolk Lipids for Tumor-Targeted Delivery of Therapeutics. Tang Z et al., 2020 Feb 19, ACS Appl Mater InterfacesRead more
- Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization. Yang Y et al., 2021 Jan, BiomaterialsRead more