GTX12996 IHC-P Image
Frizzled 7 antibody
GTX12996
ApplicationsELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Hamster, Human, Mammals, Monkey, Mouse, Rabbit, Rat
Overview
- SupplierGeneTex
- Product NameFrizzled 7 antibody
- Delivery Days Customer10
- ApplicationsELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- HostRabbit
- IsotypeIgG
- Scientific DescriptionMembers of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Canine, Hamster, Human, Mammals, Monkey, Mouse, Rabbit, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203