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GTX101881 WB Image
GTX101881 WB Image
GTX101881 WB Image

GAD67 antibody

Research Use Only
GTX101881
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    GAD67 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.57 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • ACE2 modulates glucose homeostasis through GABA signaling during metabolic stress. Ma X et al., 2020 Sep, J Endocrinol
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  • Age-related Changes in Auditory Cortex Without Detectable Peripheral Alterations: A Multi-level Study in Sprague-Dawley Rats. Occelli F et al., 2019 Apr 15, Neuroscience
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  • Loss of phenotype of parvalbumin interneurons in rat prefrontal cortex is involved in antidepressant- and propsychotic-like behaviors following acute and repeated ketamine administration. Zhou Z et al., 2015 Apr, Mol Neurobiol
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  • Neural network disturbance in the medial prefrontal cortex might contribute to cognitive impairments induced by neuroinflammation. Ji MH et al., 2020 Oct, Brain Behav Immun
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  • Two Groups of eGFP-Expressing Neurons with Distinct Characteristics in the Neocortex of GIN Mice. Wang C et al., 2019 Apr 15, Neuroscience
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