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GTX104602 WB Image
GTX104602 WB Image
GTX104602 WB Image

GALNT6 antibody [N1C2]

Research Use Only
GTX104602
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    GALNT6 antibody [N1C2]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.79 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Glycosyltransferases as Markers for Early Tumorigenesis. Andergassen U et al., 2015, Biomed Res Int
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  • Role of N-acetylgalactosaminyltransferase 6 in early tumorigenesis and formation of metastasis. Liesche F et al., 2016 May, Mol Med Rep
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