Overview
- SupplierGeneTex
- Product NameGCLM antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.33 mg/ml
- IsotypeIgG
- Scientific DescriptionGlutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Choi EJ et al., 2017 Sep 14, OncogeneRead more
- Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities. Hori Y et al., 2021 May 3, CellsRead more
- Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway. Wu YL et al., 2018 Feb 1, Free Radic Biol MedRead more
- Mechanisms of Fasting-Mediated Protection against Renal Injury and Fibrosis Development after Ischemic Acute Kidney Injury. Rojas-Morales P et al., 2019 Aug 22, BiomoleculesRead more
- Physiological cyclic strain promotes endothelial cell survival via the induction of heme oxygenase-1. Liu XM et al., 2013 Jun 15, Am J Physiol Heart Circ PhysiolRead more
- Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 Signaling. Wu CT et al., 2019, Oxid Med Cell LongevRead more
- Sulforaphane Inhibits HIV Infection of Macrophages through Nrf2. Furuya AK et al., 2016 Apr, PLoS PathogRead more
- The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated alpha-MSH in keratinocytes via Nrf2-mediated antioxidant pathways. Hseu YC et al., 2021 Aug, Redox BiolRead more
- The Protective Effect of Hispidin against Hydrogen Peroxide-Induced Oxidative Stress in ARPE-19 Cells via Nrf2 Signaling Pathway. Huang SY et al., 2019 Aug 19, BiomoleculesRead more