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GTX114075 WB Image
GTX114075 WB Image
GTX114075 WB Image

GCLM antibody

Research Use Only
GTX114075
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    GCLM antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.33 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Choi EJ et al., 2017 Sep 14, Oncogene
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  • Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities. Hori Y et al., 2021 May 3, Cells
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  • Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway. Wu YL et al., 2018 Feb 1, Free Radic Biol Med
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  • Mechanisms of Fasting-Mediated Protection against Renal Injury and Fibrosis Development after Ischemic Acute Kidney Injury. Rojas-Morales P et al., 2019 Aug 22, Biomolecules
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  • Physiological cyclic strain promotes endothelial cell survival via the induction of heme oxygenase-1. Liu XM et al., 2013 Jun 15, Am J Physiol Heart Circ Physiol
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  • Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 Signaling. Wu CT et al., 2019, Oxid Med Cell Longev
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  • Sulforaphane Inhibits HIV Infection of Macrophages through Nrf2. Furuya AK et al., 2016 Apr, PLoS Pathog
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  • The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated alpha-MSH in keratinocytes via Nrf2-mediated antioxidant pathways. Hseu YC et al., 2021 Aug, Redox Biol
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  • The Protective Effect of Hispidin against Hydrogen Peroxide-Induced Oxidative Stress in ARPE-19 Cells via Nrf2 Signaling Pathway. Huang SY et al., 2019 Aug 19, Biomolecules
    Read more