Overview
- SupplierGeneTex
- Product NameGDF5 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.65 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- GDF5 regulates TGFbeta-dependent angiogenesis in breast carcinoma MCF-7 cells: in vitro and in vivo control by anti-TGFbeta peptides. Margheri F et al., 2012, PLoS OneRead more
- Nonviral Gene Delivery of Growth and Differentiation Factor 5 to Human Mesenchymal Stem Cells Injected into a 3D Bovine Intervertebral Disc Organ Culture System. Bucher C et al., 2013, Stem Cells IntRead more