GDNF Receptor alpha 2 antibody [11G34]
GTX52762
Overview
- SupplierGeneTex
- Product NameGDNF Receptor alpha 2 antibody [11G34]
- Delivery Days Customer10
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID11G34
- Concentration500 ug/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionGlial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203