GFAP antibody, PAb

Biorbyt

GFAP antibody, PAb

10

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry

Western blot - 0.1-0.5 μg/ml - Human, Mouse, Rat - - - Immunohistochemistry(Paraffin-embedded Section) - 0.5-1 μg/ml - Rat - Mouse - By Heat Immunofluorescence - 2 μg/ml - Mouse - IF, WB, IHC

Research Use Only

Polyclonal

500 ug/ml

Rabbit

IgG

Rabbit Polyclonal to GFAP. Glial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow.

Chicken, Human, Mouse, Rat

2°C to 8°C,-20°C

12352203