GTX104362 IHC-P Image
GTX104362 IHC-P Image
GLI3 antibody
GTX104362
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameGLI3 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Blockade of Hedgehog Signaling Attenuates Biliary Cystogenesis in the Polycystic Kidney (PCK) Rat. Sato Y et al., 2018 Oct, Am J PatholRead more
- Differential Effects of Toll-Like Receptor Activation and Differential Mediation by MAP Kinases of Immune Responses in Microglial Cells. Kwon J et al., 2021 Jul 23, Cell Mol NeurobiolRead more
- GANT61 and Lithium Chloride Inhibit the Growth of Head and Neck Cancer Cell Lines Through the Regulation of GLI3 Processing by GSK3beta. Zubcic V et al., 2020 Sep 3, Int J Mol SciRead more
- Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis. Matz-Soja M et al., 2016 May 17, ElifeRead more
- Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels. Matz-Soja M et al., 2014 Feb 18, Cell Commun SignalRead more