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ProductsBack/Glypican 1 antibody [N3C3]

Glypican 1 antibody [N3C3]

Research Use Only
GTX104557
GeneTex
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Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    Glypican 1 antibody [N3C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.33 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A glypican-1-targeted antibody-drug conjugate exhibits potent tumor growth inhibition in glypican-1-positive pancreatic cancer and esophageal squamous cell carcinoma. Munekage E et al., 2021 Sep, Neoplasia
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  • Abnormal ER quality control of neural GPI-anchored proteins via dysfunction in ER export processing in the frontal cortex of elderly subjects with schizophrenia. Kim P et al., 2019 Jan 16, Transl Psychiatry
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  • Differential expression of glypican-1 in ameloblastoma variants. Bologna-Molina R et al., 2015 Feb, Appl Immunohistochem Mol Morphol
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  • Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma. Lu H et al., 2017 Jun, Cancer Med
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  • Increased secretion of VEGF-C from SiO2-induced pulmonary macrophages promotes lymphangiogenesis through the Src/eNOS pathway in silicosis. Zhang J et al., 2021 Apr 29, Ecotoxicol Environ Saf
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  • Oncogenic and Non-Malignant Pancreatic Exosome Cargo Reveal Distinct Expression of Oncogenic and Prognostic Factors Involved in Tumor Invasion and Metastasis. Emmanouilidi A et al., 2019 Apr, Proteomics
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  • Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro. Hsia K et al., 2017 Mar 15, Acta Biomater
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  • alpha3 Chains of type V collagen regulate breast tumour growth via glypican-1. Huang G et al., 2017 Jan 19, Nat Commun
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