Granzyme B antibody [14G13]
GTX53429
Overview
- SupplierGeneTex
- Product NameGranzyme B antibody [14G13]
- Delivery Days Customer10
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID14G13
- Concentration500 ug/ml
- HostRat
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis. [provided by RefSeq, Sep 2016]
- ReactivityMouse
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203