GTX108414 WB Image
GTX108414 WB Image
GREM2 antibody [C1C3]
GTX108414
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameGREM2 antibody [C1C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.26 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Coordinated Proliferation and Differentiation of Human-Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Depend on Bone Morphogenetic Protein Signaling Regulation by GREMLIN 2. Bylund JB et al., 2017 May 1, Stem Cells DevRead more
- Effects of gremlin-2 on the transition of primordial follicles during early folliculogenesis in the human ovary. Ikeda Y et al., 2016 Aug, Eur J Obstet Gynecol Reprod BiolRead more
- Gremlin 2 suppresses differentiation of stem/progenitor cells in the human skin. Kawagishi-Hotta M et al., 2021 Dec, Regen TherRead more
- Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis. Kawagishi-Hotta M et al., 2019 Dec, Regen TherRead more