GTX113340 WB Image
GTX113340 WB Image
Grp78 antibody
GTX113340
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameGrp78 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.75 mg/ml
- IsotypeIgG
- Scientific DescriptionWhen Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as immunoglobulin heavy chain-binding protein (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Achromatopsia mutations target sequential steps of ATF6 activation. Chiang WC et al., 2017 Jan 10, Proc Natl Acad Sci U S ARead more
- Acute Heat Stress Changes Protein Expression in the Testes of a Broiler-Type Strain of Taiwan Country Chickens. Wang SH et al., 2019 Apr, Anim BiotechnolRead more
- Aerobic glycolysis supports hepatitis B virus protein synthesis through interaction between viral surface antigen and pyruvate kinase isoform M2. Wu YH et al., 2021 Mar, PLoS PathogRead more
- Anti-esophageal Cancer Effect of Corilagin Extracted from Phmllanthi Fructus via the Mitochondrial and Endoplasmic Reticulum Stress Pathways. Wu C et al., 2021 Apr 6, J EthnopharmacolRead more
- Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen species. Lee CW et al., 2019 Aug, J Cell PhysiolRead more
- ATF6 is required for efficient rhodopsin clearance and retinal homeostasis in the P23H rho retinitis pigmentosa mouse model. Lee EJ et al., 2021 Aug 11, Sci RepRead more
- Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy. Huang CY et al., 2020 Jun 10, NutrientsRead more
- Bisphenol A stabilizes Nrf2 via Ca2+ influx by direct activation of the IP3 receptor. Oguro A et al., 2021, J Toxicol SciRead more
- Dehydrocostus lactone inhibits cell proliferation and induces apoptosis by PI3K/Akt/Bad and ERS signalling pathway in human laryngeal carcinoma. Zhang R et al., 2020 Jun, J Cell Mol MedRead more
- Development of a multifunctional luciferase reporters system for assessing endoplasmic reticulum-targeting photosensitive compounds. Lin S et al., 2014 Nov, Cell Stress ChaperonesRead more