GTX102580 IP Image
GTX102580 IP Image
Grp78 antibody [N2C1], Internal
GTX102580
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameGrp78 antibody [N2C1], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.28 mg/ml
- IsotypeIgG
- Scientific DescriptionWhen Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as immunoglobulin heavy chain-binding protein (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Metformin attenuates the D-galactose-induced aging process via the UPR through the AMPK/ERK1/2 signaling pathways. Cai H et al., 2020 Mar, Int J Mol MedRead more
- Periodontal disease level-butyric acid amounts locally administered in the rat gingival mucosa induce ER stress in the systemic blood. Cueno ME et al., 2016 May, Microb PathogRead more
- Placental Alkaline Phosphatase Promotes Zika Virus Replication by Stabilizing Viral Proteins through BIP. Chen J et al., 2020 Sep 15, mBioRead more
- The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKbeta/AMPK pathways. Chen X et al., 2017 Aug, Redox BiolRead more
- The unfolded protein response modulates the autophagy-mediated egg production in the mosquito Aedes aegypti. Weng SC et al., 2020 Aug, Insect Mol BiolRead more