GTX48633 FACS Image
Grp78 antibody
GTX48633
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityBovine, C. Elegans, Chicken, Drosophila, Human, Mouse, Primate, Rat, Sheep, Zebra Fish
Overview
- SupplierGeneTex
- Product NameGrp78 antibody
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- HostRabbit
- IsotypeIgG
- Scientific DescriptionWhen Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as immunoglobulin heavy chain-binding protein (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]
- ReactivityBovine, C. Elegans, Chicken, Drosophila, Human, Mouse, Primate, Rat, Sheep, Zebra Fish
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Inhibition of endoplasmic reticulum stress-related autophagy attenuates MCLR-induced apoptosis in zebrafish testis and mouse TM4 cells. Wu Z et al., 2021 Sep 15, Ecotoxicol Environ SafRead more