Overview
- SupplierGeneTex
- Product NameGSK3 beta antibody [C1C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.57 mg/ml
- IsotypeIgG
- Scientific DescriptionGlycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase (see GYS1, MIM 138570). Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets. Lin HC et al., 2017 Jan 11, J Agric Food ChemRead more
- Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3beta-beta-Catenin and XIAP-Survivin Pathways. Chang YX et al., 2020 Dec 21, Cancers (Basel)Read more
- LncRNA TTN-AS1/miR-134-5p/PAK3 axis regulates the radiosensitivity of human large intestine cancer cells through the P21 pathway and AKT/GSK-3beta/beta-catenin pathway. Zuo Z et al., 2020 Nov, Cell Biol IntRead more
- miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer. Liu J et al., 2017 Nov, Oncol LettRead more
- Moscatilin Ameliorates Tau Phosphorylation and Cognitive Deficits in Alzheimers Disease Models. Huang JM et al., 2019 Jul 26, J Nat ProdRead more
- Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis. Samuel M et al., 2021 Jun 24, Nat CommunRead more
- PAK1 confers chemoresistance and poor outcome in non-small cell lung cancer via beta-catenin-mediated stemness. Chen MJ et al., 2016 Oct 7, Sci RepRead more
- Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Xu YM et al., 2016 Feb 2, OncotargetRead more
- Radiation sensitization of tumor cells induced by shear stress: the roles of integrins and FAK. Luo CW et al., 2014 Sep, Biochim Biophys ActaRead more
- Sclareol ameliorated ERCC1-mediated cisplatin resistance in A549 human lung adenocarcinoma cells and a murine xenograft tumor model by suppressing AKT-GSK3beta-AP1/Snail and JNK-AP1 pathways. Pan CH et al., 2020 Dec 1, Chem Biol InteractRead more