GTX113727 ICC/IF Image
HADHA antibody [N2C1], Internal
GTX113727
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameHADHA antibody [N2C1], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.37 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Adipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress-induced inflammation. Lee J et al., 2015 Jan 13, Cell RepRead more
- Chemical-genetic induction of Malonyl-CoA decarboxylase in skeletal muscle. Rodriguez S et al., 2014 Aug 25, BMC BiochemRead more
- Gan-Jiang-Ling-Zhu decoction alleviates hepatic steatosis in rats by the miR-138-5p/CPT1B axis. Dang Y et al., 2020 Jul, Biomed PharmacotherRead more
- Hepatic Fatty Acid Oxidation Restrains Systemic Catabolism during Starvation. Lee J et al., 2016 Jun 28, Cell RepRead more
- Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence. Harel M et al., 2019 Sep 19, CellRead more