Overview
- SupplierGeneTex
- Product NameHDAC2 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.16 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine. Lee KH et al., 2014 Sep 17, Sci RepRead more
- A Tangeretin Derivative Inhibits the Growth of Human Prostate Cancer LNCaP Cells by Epigenetically Restoring p21 Gene Expression and Inhibiting Cancer Stem-like Cell Proliferation. Wei GJ et al., 2019 Jul 10, AAPS JRead more
- Down-regulation of the oncogene PTTG1 via the KLF6 tumor suppressor during induction of myeloid differentiation. Chen PY et al., 2013, PLoS OneRead more
- Epigenetic regulation of the glucose transporter gene Slc2a1 by beta-hydroxybutyrate underlies preferential glucose supply to the brain of fasted mice. Tanegashima K et al., 2017 Jan, Genes CellsRead more
- HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells. Huang WT et al., 2017, Front PharmacolRead more
- Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells. Chen CY et al., 2020, Front OncolRead more
- Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells. Lee JY et al., 2016, Front PharmacolRead more
- NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death. Huang D et al., 2018 Oct, Nat ImmunolRead more
- Pinostrobin Inhibits Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) Gene Expression through the Modulation of FoxO3a Protein in HepG2 Cells. Gao WY et al., 2018 Jun 20, J Agric Food ChemRead more
- Tanshinone IIA Modulates Low Density Lipoprotein Uptake via Down-Regulation of PCSK9 Gene Expression in HepG2 Cells. Chen HC et al., 2016, PLoS OneRead more