Overview
- SupplierGeneTex
- Product NameHec1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.46 mg/ml
- IsotypeIgG
- Scientific DescriptionHEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, PhytomedicineRead more
- Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1. Huang LY et al., 2014 Jan 9, J Exp Clin Cancer ResRead more
- Discovery of 4-aryl-N-arylcarbonyl-2-aminothiazoles as Hec1/Nek2 inhibitors. Part I: optimization of in vitro potencies and pharmacokinetic properties. Lee YS et al., 2014 May 22, J Med ChemRead more