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Hec1 (phospho Ser 165) antibody

Research Use Only
GTX70013
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mammals, Mouse, Rat
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More than 130 suppliers
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Overview

  • Supplier
    GeneTex
  • Product Name
    Hec1 (phospho Ser 165) antibody
  • Delivery Days Customer
    10
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.127 mg/ml
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Scientific Description
    This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]
  • Reactivity
    Human, Mammals, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint. Wei R et al., 2011 Oct, Mol Biol Cell
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  • Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity. Fang Y et al., 2016 Nov 29, Oncotarget
    Read more