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GTX130167 WB Image
GTX130167 WB Image
GTX130167 WB Image

HERC5 antibody

Research Use Only
GTX130167
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    HERC5 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    3.96 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Induced TRIM21 ISGylation by IFN-beta enhances p62 ubiquitination to prevent its autophagosome targeting. Jin J et al., 2021 Jul 13, Cell Death Dis
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