HIF-1 Alpha Polyclonal Antibody

Catalog number: BS-0737R
Brand: Bioss Antibodies
Packing: 100 ul
Price: € 315.00
Expected delivery time: 7 days
Quantity:
IHC-P / Human
Formalin-fixed and paraffin embedde...
WB / Mouse
L1 mouse heart lysates, L2 mouse la...
IF(ICC) / Others
KLN 205 cells labeled with Rabbit H...
WB / Rat
Image kindly submitted by Edita Aks...
WB / Human
HL-60 cell lysates probed with Anti...
FCM / Human
HeLa cells probed with HIF-1 Alpha ...

Product specifications for - HIF-1 Alpha Polyclonal Antibody

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: western blot, immunohistochemistry-paraffin, IF(IHC-P), IF(ICC)
Application note: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
Species: Human, Mouse, Rat
Host: Rabbit
Target: HIF1A
Target description: hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Source: KLH conjugated synthetic peptide derived from human of human HIF-1 Alpha
Properties: 
Purity: Purified by Protein A.
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1ug/ul
Form supplied: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage instructions: Store at -20°C for 12 months.
Scientific information: 
Scientific info: Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 4 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth fac
Gene ID: 3091
Swiss prot ID: Q16665
Additional information: 
Synonyms: BS-0737R; HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; Hypoxia-inducible factor 1-alpha; HIF-1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; Member of PAS protein 1; PAS domain-containing protein 8; HIF1A
Fan, Shengjun, et al. "Opposite angiogenic outcome of curcumin against ischemia and Lewis lung cancer models:in silico, in vitro and in vivo studies." Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease (2014). Read more
Guo, Wei, et al. "Transplantation of endothelial progenitor cells in treating rats with IgA nephropathy." BMC Nephrology 15.1 (2014): 110. Read more
Zhang, Huimin, et al. "Vascular Normalization Induced by Sinomenine Hydrochloride Results in Suppressed Mammary Tumor Growth and Metastasis." Scientific Reports 5 (2015). Read more
Woolf, Eric C., et al. "The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma Model." PLOS ONE10.6 (2015): e0130357. Read more
Madka, Venkateshwar, et al. "Targeting mTOR and p53 signaling inhibits muscle invasive bladder cancer in vivo." Cancer Prevention Research 9.1 (2016): 53-62. Read more
Yang, Jinjiang, Ying Lu, and Ai Guo. "Platelet-rich plasma protects rat chondrocytes from interleukin-1beta-induced apoptosis." Molecular Medicine Reports 14.5 (2016): 4075-4082. Read more
Talwar, Harvinder, et al. "MKP-1 negatively regulates LPS-mediated IL-1beta production through p38 activation and HIF-1alpha expression." Cellular Signalling (2017). Read more
Yang, Ya, et al. "Expression of RAP1B is associated with poor prognosis and promotes an aggressive phenotype in gastric cancer." Oncology reports 34.5 (2015): 2385-2394. Read more
Talwar, Harvinder, et al. "The dataset describes: HIF-1 alpha expression and LPS mediated cytokine production in MKP-1 deficient bone marrow derived murine macrophages." Data in Brief (2017). Read more
Shou, Zhu, et al. "Expression and prognosis of FOXO3a and HIF-1?? in nasopharyngeal carcinoma."Journal of cancer research and clinical oncology 138.4 (2012): 585-593. Read more