GTX30115 WB Image
HIF1 alpha antibody [H1alpha67] - Orthogonal Validated
GTX30115
ApplicationsGel Shift Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAvian, Bovine, Canine, Ferret, Human, Monkey, Mouse, Porcine, Primate, Rat, Sheep
Overview
- SupplierGeneTex
- Product NameHIF1 alpha antibody [H1alpha67] - Orthogonal Validated
- Delivery Days Customer10
- ApplicationsGel Shift Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDH1alpha67
- Concentration1 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionHypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]
- ReactivityAvian, Bovine, Canine, Ferret, Human, Monkey, Mouse, Porcine, Primate, Rat, Sheep
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Hypoxia-induced abrogation of contact-dependent inhibition of rheumatoid arthritis synovial fibroblast proliferation. Nonomura Y et al., 2009 Apr, J RheumatolRead more
- Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I. Catrina SB et al., 2006 Aug 1, Clin Cancer ResRead more