GTX33617 IHC-P Image
HIF1 alpha antibody [RM242] - Orthogonal Validated
GTX33617
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
Overview
- SupplierGeneTex
- Product NameHIF1 alpha antibody [RM242] - Orthogonal Validated
- Delivery Days Customer10
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM242
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
- ReactivityHuman, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Pre-conditioning with CDP-choline attenuates oxidative stress-induced cardiac myocyte death in a hypoxia/reperfusion model. Gonzalez-Pacheco H et al., 2014, ScientificWorldJournalRead more