GTX30123 WB Image
GTX30123 WB Image
HIF2 alpha antibody [ep190b] - Orthogonal Validated
GTX30123
ApplicationsGel Shift Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHamster, Human, Mouse, Rat
Overview
- SupplierGeneTex
- Product NameHIF2 alpha antibody [ep190b] - Orthogonal Validated
- Delivery Days Customer10
- ApplicationsGel Shift Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDep190b
- Concentration1 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionThis gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq]
- ReactivityHamster, Human, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress. Myers K et al., 2009 Jan, PLoS GenetRead more
- Changes in cell fate determine the regenerative and functional capacity of the developing kidney before and after release of obstruction. Nagalakshmi VK et al., 2018 Dec 12, Clin Sci (Lond)Read more
- Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I. Catrina SB et al., 2006 Aug 1, Clin Cancer ResRead more
- Identification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinoma. Wright TM et al., 2010 Apr 23, J Biol ChemRead more
- Thiamine deficiency activates hypoxia inducible factor-1alpha to facilitate pro-apoptotic responses in mouse primary astrocytes. Zera K et al., 2017, PLoS OneRead more
- VHL and PTEN loss coordinate to promote mouse liver vascular lesions. Chen S et al., 2010 Mar, AngiogenesisRead more
- VHL type 2B mutations retain VBC complex form and function. Hacker KE et al., 2008, PLoS OneRead more