Histone H1 Antibody
ORB533994
Overview
- SupplierBiorbyt
- Product NameHistone H1 Antibody
- Delivery Days Customer16
- ApplicationsFlow Cytometry
- Applications SupplierFlow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RTPrediluted IHC only format: incubate for 30 min at RT (1) FACS, IF, IHC-P
- CertificationResearch Use Only
- Clone IDOSHT-3R
- IsotypeIgG
- Scientific DescriptionFive major families of histones exist: H1/H5, H2A, H2B, H3, and H4. Histones H2A, H2B, H3 and H4 are known as the core histones, while histones H1/H5 are known as the linker histones. The core histones all exist as dimers, which are similar in that they all possess the histone fold domain; three alpha helices linked by two loops. It is this helical structure that allows for interaction between distinct dimers, particularly in a head-tail fashion (also called the handshake motif). The linker histone H1 binds the nucleosome at the entry and exit sites of the DNA, thus locking the DNA into place and allowing the formation of higher order structure. [Wiki]
- UNSPSC12352203