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HLA-DOA antibody [N1C3]

Research Use Only
GTX114470
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    HLA-DOA antibody [N1C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.64 mg/ml
  • Isotype
    IgG
  • Scientific Description
    HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection. Ningappa M et al., 2016 Feb, Am J Transplant
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  • Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis. Yoon T et al., 2012 Jul 10, Proc Natl Acad Sci U S A
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