Bio-Connect

HLA-DR Antibody (MHC II)

Research Use Only
ORB317068
Biorbyt
ApplicationsFlow Cytometry
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    HLA-DR Antibody (MHC II)
  • Delivery Days Customer
    16
  • Applications
    Flow Cytometry
  • Applications Supplier
    Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT FACS, IF, IHC-P
  • Certification
    Research Use Only
  • Clone ID
    19-26.1 or MB-26.1
  • Isotype
    IgG
  • Scientific Description
    This mAb reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
  • UNSPSC
    12352203