Overview
- SupplierGeneTex
- Product NameHMGA1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.87 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays. Su L et al., 2020 Nov 2, Sci RepRead more