Overview
- SupplierGeneTex
- Product NameHMGB1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.46 mg/ml
- IsotypeIgG
- Scientific DescriptionDNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- N-(2-Hydroxyphenyl)-2-Propylpentanamide (HO-AAVPA) Inhibits HDAC1 and Increases the Translocation of HMGB1 Levels in Human Cervical Cancer Cells. Sixto-Lopez Y et al., 2020 Aug 16, Int J Mol SciRead more
- N-(2-Hydroxyphenyl)-2-propylpentanamide (OH-VPA), a histone deacetylase inhibitor, induces the release of nuclear HMGB1 and modifies ROS levels in HeLa cells. Contis-Montes de Oca A et al., 2018 Sep 7, OncotargetRead more
- Alternatively activated macrophages are associated with the alpha2AP production that occurs with the development of dermal fibrosis : The role of alternatively activated macrophages on the development of fibrosis. Kanno Y et al., 2020 Apr 10, Arthritis Res TherRead more
- Amitriptyline pharmacologically preconditions rat hearts against cardiac ischemic-reperfusion injury. Lee SM et al., 2015, Int J CardiolRead more
- ASC filament formation serves as a signal amplification mechanism for inflammasomes. Dick MS et al., 2016 Jun 22, Nat CommunRead more
- Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux. Ruehl S et al., 2015 Oct, Eur J ImmunolRead more
- Dual therapeutic functions of F-5 fragment in burn wounds: preventing wound progression and promoting wound healing in pigs. Bhatia A et al., 2016, Mol Ther Methods Clin DevRead more
- Heparanase regulates the M1 polarization of renal macrophages and their crosstalk with renal epithelial tubular cells after ischemia/reperfusion injury. Masola V et al., 2018 Feb, FASEB JRead more
- High-mobility group box 1 expression and lymph node metastasis in intrahepatic cholangiocarcinoma. Xu YF et al., 2015 Mar 21, World J GastroenterolRead more
- HMGB1/IL-1beta complexes regulate neuroimmune responses in alcoholism. Coleman LG Jr et al., 2018 Aug, Brain Behav ImmunRead more