Bio-Connect
GTX101277 ICC/IF Image
GTX101277 ICC/IF Image
GTX101277 ICC/IF Image

HMGB1 antibody

Research Use Only
GTX101277
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    HMGB1 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.46 mg/ml
  • Isotype
    IgG
  • Scientific Description
    DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • N-(2-Hydroxyphenyl)-2-Propylpentanamide (HO-AAVPA) Inhibits HDAC1 and Increases the Translocation of HMGB1 Levels in Human Cervical Cancer Cells. Sixto-Lopez Y et al., 2020 Aug 16, Int J Mol Sci
    Read more
  • N-(2-Hydroxyphenyl)-2-propylpentanamide (OH-VPA), a histone deacetylase inhibitor, induces the release of nuclear HMGB1 and modifies ROS levels in HeLa cells. Contis-Montes de Oca A et al., 2018 Sep 7, Oncotarget
    Read more
  • Alternatively activated macrophages are associated with the alpha2AP production that occurs with the development of dermal fibrosis : The role of alternatively activated macrophages on the development of fibrosis. Kanno Y et al., 2020 Apr 10, Arthritis Res Ther
    Read more
  • Amitriptyline pharmacologically preconditions rat hearts against cardiac ischemic-reperfusion injury. Lee SM et al., 2015, Int J Cardiol
    Read more
  • ASC filament formation serves as a signal amplification mechanism for inflammasomes. Dick MS et al., 2016 Jun 22, Nat Commun
    Read more
  • Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux. Ruehl S et al., 2015 Oct, Eur J Immunol
    Read more
  • Dual therapeutic functions of F-5 fragment in burn wounds: preventing wound progression and promoting wound healing in pigs. Bhatia A et al., 2016, Mol Ther Methods Clin Dev
    Read more
  • Heparanase regulates the M1 polarization of renal macrophages and their crosstalk with renal epithelial tubular cells after ischemia/reperfusion injury. Masola V et al., 2018 Feb, FASEB J
    Read more
  • High-mobility group box 1 expression and lymph node metastasis in intrahepatic cholangiocarcinoma. Xu YF et al., 2015 Mar 21, World J Gastroenterol
    Read more
  • HMGB1/IL-1beta complexes regulate neuroimmune responses in alcoholism. Coleman LG Jr et al., 2018 Aug, Brain Behav Immun
    Read more