Overview
- SupplierGeneTex
- Product NamehnRNP A2B1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.2 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- hnRNPs and ELAVL1 cooperate with uORFs to inhibit protein translation. Zhang J et al., 2016 Oct 26, Nucleic Acids ResRead more
- Proteomic analysis of Antrodia Cinnamomea-induced ER stress in liver cancer cells. Chen JF et al., 2020 Aug 5, J Pharm Biomed AnalRead more
- Proteomic analysis of evodiamine-induced cytotoxicity in thyroid cancer cells. Yu HI et al., 2018 Oct 25, J Pharm Biomed AnalRead more
- Resources for the Comprehensive Discovery of Functional RNA Elements. Sundararaman B et al., 2016 Mar 17, Mol CellRead more
- RNA Binding Motif Protein RBM45 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19 through Binding to Novel Intron Splicing Enhancers. Wang J et al., 2020 Mar 10, mBioRead more
- Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Fang MY et al., 2019 Sep 4, NeuronRead more