Hsp40 (YDJ1) antibody, MAb (RPE)
ORB147335
ApplicationsImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityYeast
Overview
- SupplierBiorbyt
- Product NameHsp40 (YDJ1) antibody, MAb (RPE)
- Delivery Days Customer10
- ApplicationsImmunoPrecipitation, Western Blot, ELISA
- Applications SupplierWB (1:2000) ELISA, IP, WB
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1G10.H8
- Concentration1 mg/ml
- ConjugateRPE
- HostMouse
- IsotypeIgG1
- Scientific DescriptionMouse monoclonal to Hsp40, YDJ1 (RPE). Human Hsp40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of Hsp40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding. , type II does not. Members of the Hsp40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. Hsp40 stimulates the ATPase activity of Hsp70 which in turn causes conformational changes of the unfolded proteins . The Hsp40-Hsp70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1..
- ReactivityYeast
- Storage Instruction2°C to 8°C
- UNSPSC12352203