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Hsp40 (YDJ1) antibody, MAb (RPE)

Research Use Only
ORB147335
Biorbyt
ApplicationsImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityYeast
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    Hsp40 (YDJ1) antibody, MAb (RPE)
  • Delivery Days Customer
    10
  • Applications
    ImmunoPrecipitation, Western Blot, ELISA
  • Applications Supplier
    WB (1:2000) ELISA, IP, WB
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1G10.H8
  • Concentration
    1 mg/ml
  • Conjugate
    RPE
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Mouse monoclonal to Hsp40, YDJ1 (RPE). Human Hsp40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of Hsp40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding. , type II does not. Members of the Hsp40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. Hsp40 stimulates the ATPase activity of Hsp70 which in turn causes conformational changes of the unfolded proteins . The Hsp40-Hsp70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1..
  • Reactivity
    Yeast
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203