Overview
- SupplierGeneTex
- Product NameHSP60 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.3 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Post mortem examination of Parkinsons disease brains suggests decline in mitochondrial biomass, reversed by deep brain stimulation of subthalamic nucleus. Mallach A et al., 2019 Jun, FASEB JRead more
- Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, PhytomedicineRead more
- ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts. Qi Y et al., 2016 Apr 19, Sci RepRead more
- Basal and stress-induced Hsp70 are modulated by ataxin-3. Reina CP et al., 2012 Nov, Cell Stress ChaperonesRead more
- Bisphenol AF promotes inflammation in human white adipocytes. Chernis N et al., 2020 Jan 1, Am J Physiol Cell PhysiolRead more
- Cadmium induces mitophagy through ROS-mediated PINK1/Parkin pathway. Wei X et al., 2014 Oct, Toxicol Mech MethodsRead more
- Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis. Perez-Rodriguez S et al., 2020, PLoS OneRead more
- Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis. Perez-Rodriguez S et al., 2020, PLoS OneRead more
- Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis. Perez-Rodriguez S et al., 2020, PLoS OneRead more
- Ethyl Acetate Extract of Scindapsus cf. hederaceus Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress. Chou CK et al., 2018 Jun 21, Int J Mol SciRead more