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GTX110089 WB Image
GTX110089 WB Image
GTX110089 WB Image

HSP60 antibody

Research Use Only
GTX110089
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    HSP60 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.3 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Post mortem examination of Parkinsons disease brains suggests decline in mitochondrial biomass, reversed by deep brain stimulation of subthalamic nucleus. Mallach A et al., 2019 Jun, FASEB J
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  • Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, Phytomedicine
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  • ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts. Qi Y et al., 2016 Apr 19, Sci Rep
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  • Basal and stress-induced Hsp70 are modulated by ataxin-3. Reina CP et al., 2012 Nov, Cell Stress Chaperones
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  • Bisphenol AF promotes inflammation in human white adipocytes. Chernis N et al., 2020 Jan 1, Am J Physiol Cell Physiol
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  • Cadmium induces mitophagy through ROS-mediated PINK1/Parkin pathway. Wei X et al., 2014 Oct, Toxicol Mech Methods
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  • Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis. Perez-Rodriguez S et al., 2020, PLoS One
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  • Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis. Perez-Rodriguez S et al., 2020, PLoS One
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  • Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis. Perez-Rodriguez S et al., 2020, PLoS One
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  • Ethyl Acetate Extract of Scindapsus cf. hederaceus Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress. Chou CK et al., 2018 Jun 21, Int J Mol Sci
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